货号：E-2024057816
CAS：852808-04-9
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A112550
Chemical Name:ABT 737
Synonyms:4-[4-[(4’-Chloro[1,1’-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide;
CAS Number:852808-04-9
Molecular Formula:C₄₂H₄₅ClN₆O₅S₂
Appearance:Light Yellow to Yellow Solid
Melting Point:134-138°C (dec.)
Molecular Weight:813.43
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A selective inhibitor of BCL-2, in small cell lung cancer. ABT-737 induced dramatic regressions in tumors derived from some SCLC cell lines. Potent Bcl-2 Family inhibitor.
References:Ikegaki, N., et al.: Cancer Res., 54, 6
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