货号：E-2024063021
CAS：112683-77-9
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A641175
Chemical Name:N-(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)cyclopentanecarboxamide
CAS Number:112683-77-9
Molecular Formula:C₁₆H₂₆N₄O₃
Molecular Weight:322.4
Category:Building Blocks; Miscellaneous;
Applications:N-(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)cyclopentanecarboxamide is an intermediate in the synthesis of 8-Cyclopentyl-1,3-dipropylxanthine (C988500), a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.
References:Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008),
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