货号：E-2024063851
CAS：1227162-75-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A795305
Chemical Name:N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide
Synonyms:(S)-N-(Quinuclidin-3-yl)-5,6-dihydronaphthalene-1-carboxamide
CAS Number:1227162-75-5
Molecular Formula:C₁₈H₂₂N₂O
Appearance:White to Off-White Solid
Melting Point:153 - 157°C
Molecular Weight:282.38
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References:Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
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