货号：E-2024063932
CAS：612487-72-6
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A808085
Chemical Name:AZD1080
Synonyms:2-Hydroxy-3-(5-(morpholinomethyl)pyridin-2-yl)-1H-indole-5-carbonitrile; 2-Hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-1H-indole-5-carbonitrile; 2-Hydroxy-3-[5-[(morpholin-4-yl)methyl]pyridin-2-yl]-1H-indole-5-carbonitrile
CAS Number:612487-72-6
Molecular Formula:C₁₉H₁₈N₄O₂
Molecular Weight:334.37
Category:Research Tools;
Applications:AZD1080 is a selective, orally active, brain permeable glycogen synthase kinase-3 (GSK3) inhibitor (1,2). AZD1080 has shown to rescue synaptic plasticity deficits in rodent brain and exhibit peripheral target engagement in humans.
References:(1) Georgievska, B., et. al.: J. Neurochem., 125, 446 (2013)
(2) Chen, S., et al.: Drug Des Devel Ther. 10, 1225 (2016)
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