货号：E-2024063937
CAS：860352-01-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A808125
Chemical Name:AZD 7762
Synonyms:3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide; N-[(S)-piperidin-3-yl]amide-5-(3-Fluorophenyl)-3-ureidothiophene-2-carboxylic Acid;
CAS Number:860352-01-8
Molecular Formula:C₁₇H₁₉FN₄O₂S
Molecular Weight:362.42
Category:Standards; Enzyme Activators and Inhibitors;
Applications:AZD 7762 is studied as an cancer therapeutic agent due to its selective inhibitory activities towards checkpoint kinases, chk1 and chk2 by reversibly binding their respective ATP-binding sites within tumor cells. Recent research has also indicated AZD 7762 to possess enhancing effects towards other chk1 inhibitor lethality in glioblastoma cells.
References:Sonya, D.Z., et al.: Mol Cancer Ther., 7, 2955 (2006); Tang, D., et al.: Cancer. Bio. Ther., 13, 379 (2012);
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