货号：E-2024065080
CAS：401941-54-6
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:B200060
Chemical Name:(S)-1,4-Benzodioxan-2-carboxypiperazine
Synonyms:[(2S)-2,3-Dihydro-1,4-benzodioxin-2-yl]-1-piperazinyl-methanone
CAS Number:401941-54-6
Molecular Formula:C₁₃H₁₆N₂O₃
Appearance:White Solid
Melting Point:129-132ºC
Molecular Weight:248.28
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules;
Applications:(S)-1,4-Benzodioxan-2-carboxypiperazine is the key chiral intermediate for the synthesis of (S)-doxazosin (D537500, Mesylate salt), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
References:Fang, Q., et al.: Tetrahedron Asym., 12, 2169 (2001); Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982); de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982)
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