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TAMRA DBCO,四甲基罗丹明二苯基环辛炔,DBCO-TAMRA 可发生无铜点击化学反应

发布时间:2023-10-07 分享至:

  英文名称:DBCO-TAMRA;TAMRA-DBCO

  中文名称:四甲基罗丹明二苯基环辛炔

  分子式:C54H57N5O10

  分子量:936.09

  外观:深红色粉末

  溶解性:DMSO, DMF, DCM, THF, Chloroform

  纯度:>95% (HPLC)

  产品简介:

  TAMRA DBCO reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. This copper-free variation of click reaction overcomes a major shortcoming of copper-catalyzed click reaction – the need for copper catalyst. Copper can damage fluorescent proteins, Quantum Dot nanocyrstals, certain enzymes, and photoproteins like RPE. The presence of copper is also problematic in staining the surface of live cells.

  In application where the presence of copper is a concern TAMRA DBCO is an ideal alternative to copper requiring fluorescent alkynes.

  TAMRA DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.

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