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CAS:478081-98-0|7-(N-Ethylacetamidophenyl)-5-(N-ethylacetamidophenyl) Zaleplon

发布时间:2024-05-29 分享至:

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Catalogue Number:C982205
Chemical Name:7-(N-Ethylacetamidophenyl)-5-(N-ethylacetamidophenyl) Zaleplon
Synonyms:N-(3-(3-Cyanopyrazolo[1,5-α]pyrimidin-5-yl)phenyl)-N-ethylacetamide; USP Zaleplon Related Compound B;
CAS Number:478081-98-0
Molecular Formula:C₁₇H₁₅N₅O
Molecular Weight:305.33
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(N-[3-(3-Cyanopyrazolo[1,5-alpha]pyrimidin-5-yl)phenyl]-N-ethylacetamide) is used in the synthesis of Zaleplon (Z145000), which is a selective non-benzodiazepine GABAA receptor agonist, and a sedative-hypnotic, almost entirely used for the management/treatment of insomnia.
References:Allen, D., et al.: Eur. J. Clin. Pharmacol., 45, 313 (1993); Beer, B., et al.: J. Clin. Pharmacol., 34, 335 (1994); Rosen, A.S., et al.: Biopharm. Drug Dispos., 20, 171 (1999); Elie, R., et al.: J. Clin. Psychiatry, 60, 536 (1999); Heydorn, W.E., et al.: Expert Opin. Invest. Drugs, 9, 841 (2000);
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