生物活性：Piracetam-d8 (UCB-6215-d8) is the deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Piracetam-d8 相关抗体:
PSD95 Antibody
NMDAR1 Antibody
NMDAR2A Antibody
Ionotropic Glutamate Receptor 2 Antibody (YA1143)
GRM5 Antibody (YA1509)
Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081)
NR2E1 Antibody (YA2648)
NR2F2 Antibody (YA1223)
KA1 Antibody (YA1879)
GRIK2 Antibody (YA2705)
PSD93 Antibody (YA3187)
分子量：150.21
Formula：C6H2D8N2O2
CAS 号：1329799-64-5
非标记 CAS：7491-74-9
中文名称：吡拉西坦 d8
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (530 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Mingeot-Leclercq, M.P., et al., Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment. Biochim Biophys Acta, 2003. 1609(1): p. 28-38.
 [Content Brief]
[3]. Muller, W.E., et al., Effects of piracetam on membrane fluidity in the aged mouse, rat, and human brain. Biochem Pharmacol, 1997. 53(2): p. 135-40.
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[4]. Scheuer, K., et al., Piracetam improves cognitive performance by restoring neurochemical deficits of the aged rat brain. Pharmacopsychiatry, 1999. 32 Suppl 1: p. 10-6.
 [Content Brief]