Name:Vinblastine (NSC-49842) sulfate
Synonyms:Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe
CAS Number:143-67-9
Formula:C46H58N4O9.H2SO4
M.w.:909.05
DMSO (mg/mL)Max Solubility:100
DMSO (mM)Max Solubility:110
Form:sulfate
SMILES:CCC1(O)CC2CN(CCC3=C([NH]C4=CC=CC=C34)C(C2)(C(=O)OC)C5=C(OC)C=C6N(C)C7C(O)(C(OC(C)=O)C8(CC)C=CCN9CCC7(C89)C6=C5)C(=O)OC)C1.O[S](O)(=O)=O
ALogP:4.28
Target:AChR,Antineoplastic and Immunosuppressive Antibiotics,Apoptosis related,Autophagy,Microtubule Associated
Pathway:Cytoskeletal Signaling
Information:Vinblastine sulfate (NSC49842, Vincaleukoblastine sulfate salt, 29060-LE, Exal, Velban, Velbe) inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM in a cell-free assay, used to treat certain kinds of cancer. Vinblastine sulfate induces autophagy and apoptosis.
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