货号：E-2024050133
CAS：336784-82-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C246725
Chemical Name:Calebin A
Synonyms:(E)-4-(4-Hydroxy-3-methoxyphenyl)-2-oxobut-3-en-1-y (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate;
CAS Number:336784-82-8
Molecular Formula:C₂₁H₂₀O₇
Molecular Weight:384.38
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
Applications:Calebin A is a novel natural product of turmeric (Curcuma longa) rhizome that possess various pharmacological properties. Calebin A is a chemotherapeutic agent that suppresses cell growth, invasion and colony formation in colorectal cancer cells (CRC) by the suppression of NF-​κB signaling. Calebin A potentiates the effect of 5-FU and TNF-beta (lymphotoxin alpha) against human colorectal cancer cells and potential role of NF-kappaB.
References:Buhrmann, C., et al.: Int. J. Mol. Sci., 21, 2393 (2020); Majeed, A., et al.: J. Pure Appl. Microbiol., 13, 5636 (2019)
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