货号：E-2024050374
CAS：2484719-17-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C283810
Chemical Name:Chlorobutoxy Abiraterone
Synonyms:3-((3S,8R,9S,10R,13S,14S)-3-(4-Chlorobutoxy)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
CAS Number:2484719-17-5
Molecular Formula:C28H38ClNO
Molecular Weight:440.06
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Chlorobutoxy Abiraterone is a derivative of Abiraterone, which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References:Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);
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