货号：E-2024050424
CAS：23848-46-6
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C291945
Chemical Name:Chenodeoxycholan-24-ol
Synonyms:(3α,5β,7α)-Cholane-3,7,24-triol; 5β-Cholane-3α,7α,24-triol;
CAS Number:23848-46-6
Molecular Formula:C₂₄H₄₂O₃
Appearance:Off-white Foamy Solid
Molecular Weight:378.59
Storage:-20°C
Solubility:Dichloromethane
Category:Building Blocks; Steroids; Miscellaneous;
Applications:Chenodeoxycholan-24-ol is an intermediate used in the synthesis of 3a,7a-Dihydroxycoprostanic Acid-d3 (D452517), which is a labelled analogue of 3a,7a-Dihydroxycoprostanic Acid (D452515), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3a,7a-Dihydroxycoprostanic Acid.
References:Hanson, R. F., et al.: Science (Washington, DC, U. S.), 203, 1107 (1979)
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