货号：E-2024050433
CAS：130593-75-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C292530
Chemical Name:(3a,5b,7b)-Cholane-3,7,24-triol
Synonyms:(3R,5S,7S,8R,9S,10S,13R,14S,17R)-17-((R)-5-Hydroxypentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol; Ursodeoxycholic Acid EP Impurity I;
Impurity:Ursodeoxycholic Acid EP Impurity I
CAS Number:130593-75-8
Molecular Formula:C₂₄H₄₂O₃
Appearance:White to Off-White Solid
Melting Point:>80°C (dec.)
Molecular Weight:378.59
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3a,5b,7b)-Cholane-3,7,24-triol (Ursodeoxycholic Acid EP Impurity I) is used in the preparation of Ursodeoxycholic Acid (U850000) scaffold. Ursodeoxycholic Acid scaffold is used to generate novel and selective steroidal ligands for GP-BAR1, a promising pharmacology target for the treatment of steatohepatitis, type 2 diabetes, and obesity.
References:Sepe, V., et. al.: Sepe, V., et. al.: J. Med. Chem., 57, 7687 (2014)
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