货号：E-2024050520
CAS：345226-20-2
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C320000
Chemical Name:(2-Chloro-4-trifluoromethoxyphenyl)boronic Acid
Synonyms:2-Chloro-4-trifluoromethoxybenzeneboronic Acid
CAS Number:345226-20-2
Molecular Formula:C₇H₅BClF₃O₃
Molecular Weight:240.37
Category:Building Blocks; Miscellaneous;
Applications:(2-Chloro-4-trifluoromethoxyphenyl)boronic Acid is an intermediate used to prepare aza- and diazabiphenyl analogs of the antitubercular drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine. It is also used in the synthesis of aryl(alkylamino)nitropyridines via amination of chlorohydroxynitropyridine with aliphatic amines followed by chlorination, and Suzuki-coupling with arylboronic acids.
References:Kmentova, I., et al.: J. Med. Chem., 53, 8421 (2010); Arvanitis, A., et al.: Bioorg. Med. Chem. Lett., 13, 125 (2003)
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