货号：E-2024051413
CAS：1056459-35-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C367730
Chemical Name:5-Chloro-1-(2-fluorophenyl)pentan-2-one
Synonyms:5-Chloro-1-(2-fluorophenyl)-2-pentanone
CAS Number:1056459-35-8
Molecular Formula:C₁₁H₁₂ClFO
Molecular Weight:214.66
Category:Building Blocks; Miscellaneous;
Applications:5-Chloro-1-(2-fluorophenyl)pentan-2-one is an intermediate in the synthesis of Prasugrel (P701150). Prasugrel is a novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome.
References:Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),
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