货号：E-2024051816
CAS：1783755-80-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C371575
Chemical Name:3-Chloro-2,4-dimethyl-benzenesulfonyl Chloride
CAS Number:1783755-80-5
Molecular Formula:C₈H₈Cl₂O₂S
Appearance:White Solid
Molecular Weight:239.12
Storage:-20°C
Solubility:Ethylacetate
Category:Building Blocks; Miscellaneous;
Applications:3-Chloro-2,4-dimethyl-benzenesulfonyl Chloride is an intermediate in the synthesis of 3-Chloro-Vortioxetine (C424140) which is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
References:Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)
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