货号：E-2024052906
CAS：75511-22-7
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C429115
Chemical Name:1-​[1-​(4-​Chlorobenzoyl)​-​5-​hydroxy-​2-​methyl-​1H-​indole-​3-​acetate]b-​D-​Glucopyranuronic Acid
Synonyms:O-Desmethyl Indomethacin-acyl-β-D-glucuronide
CAS Number:75511-22-7
Molecular Formula:C₂₄H₂₂ClNO₁₀
Appearance:Pale Yellow to Beige Solid
Melting Point:>200°C (dec.)
Molecular Weight:519.89
Storage:- 86°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic, Moisture Sensitive
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-​[1-​(4-​Chlorobenzoyl)​-​5-​hydroxy-​2-​methyl-​1H-​indole-​3-​acetate]b-​D-​Glucopyranuronic Acid is an analog of Indomethacin Acyl-b-D-glucuronide a metabolite of Indomethacin (I641000). Acyl glucuronides have been implicated in the toxicity of many xenobiotics and marketed drugs.
References:Abid, A., et al.: Biochem. Pharmacol., 50, 557 (1995), Gamage, N., et al.: Toxicol. Sci., 90, 5 (2006), Cerveny, L., et al.: Drug Metab. Dispos., 35, 1032 (2007), Hayeshi, R., et al.: Eur. J. Pharm. Sci., 35, 383 (2008),
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