货号：E-2024053081
CAS：197775-85-2
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C433028
Chemical Name:5-Chloro-2-[(ethoxycarbonyl)oxy]-1H-indole-1-carboxylic Acid Ethyl Ester
Synonyms:Ethyl 5-Chloro-2-((ethoxycarbonyl)oxy)-1H-indole-1-carboxylate
CAS Number:197775-85-2
Molecular Formula:C₁₄H₁₄ClNO₅
Appearance:Brown Solid
Molecular Weight:311.72
Solubility:Dichloromethane, Ethyl Acetate, Methanol
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Chloro-2-[(ethoxycarbonyl)oxy]-1H-indole-1-carboxylic Acid Ethyl Ester is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3b inhibitors as anticancer agents.
References:Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);
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