货号：E-2024053246
CAS：1252927-45-9
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C472235
Chemical Name:N-(4-Chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine
Synonyms:(4-Chloro-pyrimidin-2-yl)-(2,3-dimethyl-2H-indazol-6-yl)-methyl-amine
CAS Number:1252927-45-9
Molecular Formula:C₁₄H₁₄ClN₅
Molecular Weight:287.75
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-(4-Chloro-2-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine is an intermediate in the synthesis of 5-((2-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-4-yl)amino)-2-methylbenzenesulfonamide Hydrochloride (D474433) which is an impurity of Pazopanib (P210925), which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References:Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009),
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