货号：E-2024053751
CAS：1203-25-4
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C595035
Chemical Name:6-Chloro-1,3-dimethyl-5-nitrouracil
Synonyms:6-Chloro-1,3-dimethyl-5-nitro-2,4(1H,3H)-pyrimidinedione; 1,3-Dimethyl-5-nitro-6-chlorouracil; 6-Chloro-1,3-dimethyl-5-nitrouracil; NSC 68157;
CAS Number:1203-25-4
Molecular Formula:C₆H₆ClN₃O₄
Molecular Weight:219.58
Category:Building Blocks; Miscellaneous;
Applications:6-Chloro-1,3-dimethyl-5-nitrouracil is an intermediate used in the synthesis of 9-​(1,​3-​Dioxolan-​2-​ylmethyl)​-​3,​9-​dihydro-​1,​3-​dimethyl-1H-​purine-​2,​6-​dione (D486860), which is an isomer impurity in the synthesis of Doxofylline (D557100), a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases.
References:Franzone, J., et al.: Drugs Exp. Clin. Res., 14, 479 (1988), Nicholson, C., et al.: Pulm. Pharmacol., 7, 1 (1994), Sullivan, P., et al.: Lancet, 343, 1006 (1994),
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