货号：E-2024054378
CAS：1246833-26-0
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C838502
Chemical Name:Curcumin-d6
Synonyms:(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione-d6; (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione-d6; C Yellow 15-d6; C.I. 75300-d6; Curcuma-d6; Curcumine-d6; Diferuloylmethane-d6; Haidr-d6; Halad-d6; Haldar-d6; Ukon-d6;
CAS Number:1246833-26-0
Alternate CAS #
458-37-7-unlabelled
Molecular Formula:C₂₁H₁₄D₆O₆
Appearance:Orange to Dark Orange Solid
Melting Point:>178°C (dec.)
Molecular Weight:374.42
Storage:4°C
Solubility:Chloroform (Slightly, Sonicated), DMSO (Slightly)
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Dyes; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Labelled Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
References:Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817
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