货号：E-2024055032
CAS：254452-88-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C988610
Chemical Name:(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt
Synonyms:ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt
CAS Number:254452-88-5
Alternate CAS #
Free Acid: 254452-86-3
Molecular Formula:C₂₅H₂₄FNO₄ •1/2Ca
Appearance:White to Off-White Solid
Melting Point:>187°C (dec.)
Molecular Weight:440.49
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt is the 3S,5R- Isomer of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent.
References:Suzukim M., et al.: Bioorg. Med. Chem., 9, 2977 (1999); Yen, H., et al.: J. Clin. Invest., 98, 1253 (1996); Zou, Y., et al.: J. Biol. Chem., 274, 9760 (1999); Sun, X., et al.: Cancer Res., et al.: 61, 3382 (2001); Ladas, E.J., et al.: Clin. Oncol., 22, 517 (2004);
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