货号：E-2024055202
CAS：1187966-93-3
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C989575
Chemical Name:(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid
Synonyms:(βR,δS)-6-Cyclopropyl-10-fluoro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid
CAS Number:1187966-93-3
Molecular Formula:C₂₅H₂₂FNO₄
Appearance:Pale Beige to Light Beige Solid
Molecular Weight:419.44
Storage:-20°C, Hygroscopic
Solubility:Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is an impurity of pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic.
References:Grobelny, P., et. al.: J. Pharmaceut. Biomed. Anal., 50, 597 (2009); Aoki, T., et al.: Arzneim.-Forsch., 47, 904 (1997); Yamada, I., et al.: Xenobiotica, 33, 789 (2003); Park, S., et al.: Clin. Ther., 27, 1074 (2005)
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