货号：E-2024055344
CAS：1046462-02-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C992010
Chemical Name:11-Cyclopropyl-5,11-dihydro-4-[[(methylsulfonyl)oxy]methyl]-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms:(11-Cyclopropyl-6-oxo-6,11-dihydro-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-4-yl)methyl methanesulfonate
CAS Number:1046462-02-5
Molecular Formula:C₁₆H₁₆N₄O₄S
Appearance:White to Light Yellow Solid
Molecular Weight:360.39
Storage:-20°C
Solubility:Chloroform, Dichloromethane, Methanol
Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:11-Cyclopropyl-5,11-dihydro-4-[[(methylsulfonyl)oxy]methyl]-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one is an intermediate in synthesizing Nevirapine-d1 (N391279), an isotope labelled Nevirapine (N391275), which acts as a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.
References:Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991); Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993); Guay, L.A., et al.: Lancet, 354, 795 (1999)
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