货号：E-2024055631
CAS：1110813-31-4
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:D101575
Chemical Name:Dacomitinib
Synonyms:PF 00299804-03; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-Butenamide
CAS Number:1110813-31-4
Molecular Formula:C₂₄H₂₅ClFN₅O₂
Appearance:White to Pale Yellow Solid
Melting Point:184-187°C
Molecular Weight:469.94
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.
References:Williams, J. et al.: PLoS., 9, e98557 (2014); Peters, S. et al.: Canc. Treatment Rev., 40, 917 (2014);
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