货号：E-2024057324
CAS：2353-16-4
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:D268420
Chemical Name:(6α,​11β)​-6,​9-​Difluoro-​11,​21-​dihydroxy-pregna-​1,​4-​diene-​3,​20-​dione
CAS Number:2353-16-4
Molecular Formula:C₂₁H₂₆F₂O₄
Molecular Weight:380.43
Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(6α,​11β)​-6,​9-​Difluoro-​11,​21-​dihydroxy-pregna-​1,​4-​diene-​3,​20-​dione is an intermediate in the synthesis of 17α,21-Dideoxy-6α,​9α-Difluoroprednisolone (D440963) which is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.
References:Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)
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