货号：E-2024057403
CAS：1807632-95-6
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:D281960
Chemical Name:4-Deschloro-4-bromo Dapagliflozin
Synonyms:(1S)-1,5-Anhydro-1-C-[4-bromo-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol; Dapagliflozin Impurity 3; (2S,3R,4R,5S,6R)-2-(4-bromo-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
CAS Number:1807632-95-6
Molecular Formula:C₂₁H₂₅BrO₆
Appearance:White to Off-White Solid
Melting Point:63 - 79°C
Molecular Weight:453.32
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Deschloro-4-bromo Dapagliflozin is an impurity of Dapagliflozin (D185370) which is a sodium-glucose transporter 2 inhibitor and used to treat type 2 diabetes.
References:Kasichayanula, S., et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Lin, T., et al.: Bioorgan. Med. Chem., 21, 6282 (2013); Rajan, S., et al.: Process for the preparation of (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (dapagliflozin) and its solvate thereof, Indian Patent 2014CH01141, Sep 11, 2015;
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