货号：E-2024058048
CAS：27489-60-7
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A158340
Chemical Name:trans-4-Acetamidocyclohexanol
Synonyms:trans-N-(4-Hydroxycyclohexyl)-acetamide;
CAS Number:27489-60-7
Molecular Formula:C₈H₁₅NO₂
Appearance:White to Off-White Solid
Melting Point:127 - 144°C
Molecular Weight:157.21
Storage:-20°C, Inert atmosphere
Solubility:Dichloromethane (Slightly, Heated), DMSO (Slightly), Methanol (Slightly), Water
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:trans-4-Acetamidocyclohexanol is an intermediate in the synthesis of 4”-trans-Hydroxy Cilostazol (H918300), a metabolite of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
References:de Morais, S., et al.: J. Biol. Chem., 269, 15419 (1994); Tata, P; J Pharm Biomed Anal, 24, 381
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