货号：E-2024058081
CAS：2095393-15-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

试剂家(www.empireagents.com) - 瑞禧生物旗下试剂品牌。致力于为全球客户提供高性价比的助力药物递送的产品服务。公司的奋斗目标是搭建一个国际知名的药物递送修饰平台，携手高端人才和所有合作伙伴，共同为人类各行各业的事业发展做出贡献！
Catalogue Number:A158920
Chemical Name:ARQ 531
Synonyms:(2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone; 1,5-Anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol
CAS Number:2095393-15-8
Molecular Formula:C₂₅H₂₃ClN₄O₄
Molecular Weight:478.93
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:ARQ 531 is a reversible non-covalent inhibitor of Bruton’s Tyrosine Kinase (BTK),with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It shows strong target inhibition in TMD8 cell line.
References:Eathiraj, et al.: Clin. Lymphoma Myeloma Leuk., 16,47(2016)
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