货号：E-2024058430
CAS：50700-49-7
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

试剂家(www.empireagents.com) - 瑞禧生物旗下试剂品牌。致力于为全球客户提供高性价比的助力药物递送的产品服务。公司的奋斗目标是搭建一个国际知名的药物递送修饰平台，携手高端人才和所有合作伙伴，共同为人类各行各业的事业发展做出贡献！
Catalogue Number:A170000
Chemical Name:N-Acetyl-4-benzoquinone Imine
Synonyms:4-(Acetylimino)-2,5-cyclohexadien-1-one; Acetimidoquinone; N-Acetyl-p-benzoquinonimine; NAPQI;
CAS Number:50700-49-7
Molecular Formula:C₈H₇NO₂
Appearance:Pale Yellow to Very Dark Orange Solid
Melting Point:>58C (dec.)
Molecular Weight:149.15
Storage:- 86°C
Solubility:Chloroform (Slightly, Sonicated), DMSO (Slightly)
Stability
Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4).
References:(1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006)
(2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)
(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)
(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)
试剂家(www.empireagents.com)从未停止过技术的拓展与创新。凭借这充满进取的创新精神，我们已经为国内外高校、科研单位、材料研究中心、生物技术制药开发公司等等定制合成了各种功能化试剂，赢得了合作单位的长期信赖。
更多产品推荐:
CAS:1346603-00-6|2-(tert-Butylamino)-3’,5’-dichloropropiophenone Hydrochloride
CAS:94-32-6|Ethyl 4-​(Butylamino)​benzoate(4-(Butylamino)benzoic Acid Ethyl Ester)
CAS:1797134-47-4|N-(tert-Butyloxycarbonyl-piperidin-4-yl)methyl-3-chloro-5-fluorobenzamide
CAS:6292-59-7|4-tert-Butylbenzenesulfonamide
CAS:5292-43-3|tert-Butyl Bromoacetate
CAS:1173022-29-1|tert-Butyl Bromoacetate-13C
CAS:355012-88-3|N-Butyldeoxymannojirimycin Hydrochloride
CAS:25013-16-5|Butylated Hydroxyanisole
CAS:4161-24-4|4-Butoxybutanol
CAS:93835-05-3|tert-Butyl β-Carboline-3-carboxylate