货号：E-2024059553
CAS：2323570-72-3
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A355335
Chemical Name:Afatinib Impurity AFT-8
Synonyms:N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide;
CAS Number:2323570-72-3
Molecular Formula:C₂₄H₂₇ClFN₅O₄
Appearance:White to Off-White Solid
Melting Point:>95°C (dec.)
Molecular Weight:503.95
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
Stability
Stable under recommended storage conditions., Stable Under Recommended Storage C
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Afatinib Impurity AFT-8 is an impurity of its parent compound Afatinib (A355300), which is an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
References:Nakao, K., et al.: Sci. Rep., 9, 18202 (2019); Ebert, K, PLoS One, 14, 0223225 (2019)
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