货号：E-2024059720
CAS：257879-35-9
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A433470
Chemical Name:3-Anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dione
Synonyms:3-(1-(3-Imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione; 3-[1-[3-(1H-Imidazol-1-yl)propyl]-1H-indol-3-yl]-4-(phenylamino)-1H-pyrrole-2,5-dione
CAS Number:257879-35-9
Molecular Formula:C₂₄H₂₁N₅O₂
Molecular Weight:411.47
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:3-Anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dion is an anilino-monoindolylmaleimide compound that acts as a potent and selective PKCβ inhibitor.3-Anilino-4-[1-(3-imidazol-1-ylpropyl)indol-3-yl]pyrrole-2,5-dione is a selective JAK3 inhibitor with selectivity over JAK2 and TYK2 for potential treatment of rheumatoid arthritis.
References:Tanaka, M., et al.: Bioorg. Med. Chem. Lett., 14, 5171 (2004); Zhao, S., et al.: Youji Huaxue, 28, 1676 (2008); McDonnell, M. E., et al.: Bioorg. Med. Chem. Lett., 24, 1116 (2014)
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