货号：E-2024060738
CAS：956025-99-3
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A602985
Chemical Name:4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine
Synonyms:3-[(3-Bromophenyl)methyl]-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-BrB-PP1;
CAS Number:956025-99-3
Molecular Formula:C₁₆H₁₈BrN₅
Appearance:White to Pale Beige Solid
Melting Point:140-142°C
Molecular Weight:360.25
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.
References:Eblen, S., et al.: J. Biol. Chem., 278, 14926 (2003), Lindsley, C., et al.: Bioorg. Med. Chem. Lett., 15, 761 (2005), Manning, B., et al.: Cell, 129, 1261 (2007), Heerding, D., et al.: J. Med. Chem., 51, 5663 (2008),
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