货号：E-2024060785
CAS：5790-69-2
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A603230
Chemical Name:2-Amino-5-chlorobenzenesulfonamide
CAS Number:5790-69-2
Molecular Formula:C₆H₇ClN₂O₂S
Appearance:Light Brown to Beige Solid
Melting Point:144-150°C
Molecular Weight:206.65
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Amino-5-chlorobenzenesulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).
References:Cannazza, G., et. al.: Bioorg. Med. Chem. Lett., 19, 1254 (2009); Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995); Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999); Sun, Y., et al.: Nature, 417, 245 (2002); Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006)
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