货号：E-2024063533
CAS：1236699-92-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A780100
Chemical Name:AS-703026
Synonyms:N-[(2S)-2,3-Dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]-4-pyridinecarboxamide;
CAS Number:1236699-92-5
Molecular Formula:C₁₅H₁₅FIN₃O₃
Molecular Weight:431.2
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor, in human multiple myeloma (MM). AS703026 induces pleiotropic anti-myeloma activity in vitro and in vivo. MEK inhibitors are useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Potent MEK inhibitor.
References:Billadeau, D., et al.: Cancer Res., 55, 3640 (1995), Kolch, W., et al.: Biochem. J., 351, 289 (2000), Smith, M., et al.: Leukemia, 17, 274 (2003), Adjei, A., et al.: J. Clin. Oncol., 26, 2139 (2008),
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