货号：DT2025060507
CAS：557794-38-4
规格：mg(更多包装需求请咨询客服)
纯度：≥98%
生产商：试剂家

生物活性：Dapsone-d8 is a deuterium labeled Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with antibacterial, antigenic and anti-inflammatory activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone can be used as an anticonvulsant and also in the research of skin and glioblastoma diseases[2][3][4][5].
体外研究(In Vitro)：氨苯砜 (0.06 mM; 30 min) 抑制 N-Formyl-Met-Leu-Phe.html" class="link-product" target="_blank">N-Formyl-Met-Leu-Phe (HY-P0224) (1 μM) 和生理激动剂 C5a (100 nM) 触发的细胞内外超氧化物 (O2-) 和胰蛋白酶 E 的释放，而不是对 Phorbol 12-myristate 13-acetate.html" class="link-product" target="_blank">Phorbol 12-myristate 13-acetate (HY-18739) (100 nM) 没有作用[5]。
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Dapsone-d8 相关抗体:
Catalase Antibody (YA552)
Catalase Antibody (YA811)
MRP2 Antibody
C Reactive Protein Antibody (YA941)
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
PU.1/SPI1 Antibody (YA1116)
PARK7/DJ1 Antibody (YA1799)
Sulfadimidine Antibody (YA906)
C Reactive Protein Antibody (YA939)
C Reactive Protein Antibody (YA940)
Elongation factor 2 Antibody (YA963)
Anthrax Protective gen Antibody (YA1060)
PON1 Antibody (YA1666)
PON2 Antibody (YA1688)
Elongation factor 1 gamma Antibody (YA2004)
Pulmonary Surfactant Associated Protein D Antibody (YA2107)
Cathelicidin Antibody (YA2380)
Elongation Factor Ts Antibody (YA2524)
Elongation Factor 1A2 Antibody (YA2879)
BPI Antibody (YA3068)
MetRS Antibody (YA3196)
体内研究(In Vivo)
氨苯砜 (5 mg/kg; i.p.; 单次给药) 具有神经保护作用，显著改进了 Scopolamine.html" class="link-product" target="_blank">Scopolamine (HY-N0296) 诱导记忆损伤小鼠的记忆获取能力[6]。
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model:
Scopolamine-induced memory impairment model in mice[6]
Dosage:
0.1, 0.3, 1, 5, and 10 mg/kg; 1 mg/kg for Scopolamine
Administration:
Intraperitoneal injection; single dose
Result:
Improved memory acquisition.
分子量：256.35
Formula：C12H4D8N2O2S
CAS 号：557794-38-4
非标记 CAS：80-08-0
性状：固体
颜色：White to off-white
中文名称：氨苯砜 d8
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month