货号：DT2025060662
CAS：1093951-85-9
规格：mg(更多包装需求请咨询客服)
纯度：≥98%
生产商：试剂家

生物活性：Deupirfenidone-d3-d3 is the deuterium labeled Pirfenidone (HY-B0673)[1].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Administration of Pirfenidone (300 mg/kg/day) for 4 wk. Pirfenidone significantly attenuates the score when administered in Bleomycin (BLM)-treated mice (P<0.0001). Moreover, collagen content is quantified in the lungs to evaluate the anti-fibrotic effects of Pirfenidone. The collagen content in the lungs of BLM-treated mice is significantly increased compared with that in saline- or Pirfenidone-treated mice, and this increase is significantly attenuated by Pirfenidone administration on day 28 after BLM treatment (P=0.0012)[5].
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
NCT NumberSponsorConditionStart DatePhaseNCT05321420PureTechIdiopathic Pulmonary FibrosisJuly 29, 2022Phase 2
分子量：188.24
Formula：C12H8D3NO
CAS 号：1093951-85-9
非标记 CAS：53179-13-8
性状：固体
颜色：White to off-white
中文名称：吡非尼酮-d3；哌非尼酮-d3；吡啡尼酮-d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month