货号：DT2025061928
CAS：1192812-66-0
规格：mg(更多包装需求请咨询客服)
纯度：≥98%
生产商：试剂家

生物活性：Metaxalone-d3 is the deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia[1][2][3][4].
IC50 & Target：PPARγ and MAO-A[4]
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Metaxalone-d3 相关抗体:
NF-KB p65 Antibody
Phospho-NF-KB p65 (Ser536) Antibody
Phospho-NF-κB p65 (Ser529) Antibody
NF-KB p65 Antibody (YA267)
NF-KB p105/p50 Antibody
RelB Antibody
Ret Antibody
Retinoic Acid Receptor alpha Antibody
SOD2 Antibody (YA071)
SOX1 Antibody
TRAF2 Antibody
Annexin A1 Antibody (YA832)
DDX3 Antibody (YA784)
NF-KB p100 Antibody
NF-KB p105 Antibody (YA700)
Nrf1 Antibody
PGC1 alpha Antibody
Phospho-NF-KB p65 (Thr254) Antibody
SOD2 Antibody (YA670)
TRAF6 Antibody
Phospho-NFKB1(Ser337) Antibody
Nrf2 Antibody(YA895)
DDIT3 Antibody
Phospho-NF-κB p65 (Ser536) Antibody
c-Rel Antibody
Annexin A10 Antibody (YA1134)
MYBBP1A Antibody (YA1387)
Retinoic Acid Receptor beta Antibody (YA1574)
Rel B Antibody (YA1852)
Retinoic Acid Receptor gamma Antibody (YA1860)
分子量：224.27
Formula：C12H12D3NO3
CAS 号：1192812-66-0
非标记 CAS：1665-48-1
性状：固体
颜色：White to off-white
中文名称：美他沙酮 d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month