货号：DT2025061946
CAS：2095569-76-7
规格：mg(更多包装需求请咨询客服)
纯度：≥98%
生产商：试剂家

生物活性：Enasidenib-d6 (AG-221-d6) is the deuterium labeled Enasidenib (HY-18690)[1]. Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively[2].
体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
试剂家 has not independently confirmed the accuracy of these methods. They are for reference only.
Enasidenib-d6 相关抗体:
IDH1 Antibody
Aconitase 2 Antibody (YA2151)
Aconitase 1 Antibody (YA2850)
分子量：479.41
Formula：C19H11D6F6N7O
CAS 号：2095569-76-7
非标记 CAS：1446502-11-9
中文名称：恩西地平-d6
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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