货号：E-2024056150
CAS：845639-07-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:D205060
Chemical Name:2-Debenzoyl Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether
Synonyms:(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid Ester;
CAS Number:845639-07-8
Molecular Formula:C₅₄H₉₁NO₁₃Si₃
Molecular Weight:1046.56
Category:Building Blocks; Standards; Chiral Molecules; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Debenzoyl Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether is an intermediate used in the synthesis of 2-Debenzoyl-2-pentenoyldocetaxel (D205050), which is a related compound of Docetaxel (D494420), a chemotherapy drug that exhibits anti-mitotic properties and used for treating various metastatic cancers.
References:Yokoyama, G., et al.: Int J Clin Oncol 10, 139 (2005); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)
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