货号：E-2024056478
CAS：842133-16-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:D228735
Chemical Name:Defluoro-Canagliflozin
Synonyms:(1S)-1,​5-​Anhydro-​1-​C-​[4-​methyl-​3-​[(5-​phenyl-​2-​thienyl)​methyl]​phenyl]​-D-​glucitol, ​,
CAS Number:842133-16-8
Molecular Formula:C₂₄H₂₆O₅S
Molecular Weight:426.53
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Defluoro-Canagliflozin is an impurity of Canagliflozin (C175190), a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
References:Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);
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