货号：E-2024061365
CAS：1350800-76-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A609975
Chemical Name:(1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one
Synonyms:Saxaglyptin Cyclic Amidine Impurity:CAS Number:1350800-76-8
Molecular Formula:C₁₈H₂₅N₃O₂
Molecular Weight:315.41
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one, is a cyclic amidine impurity of Saxagliptin (S143500), which is a potent dipeptidyl peptidase-4 inhibitor approved for the treatment of type 2 diabetes mellitus.
References:Hong, S., et al.: Drug Metabolism & Disposition, 40, 1345 (2012); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007);
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