货号：E-2024061374
CAS：1429782-93-3
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A610020
Chemical Name:(1aS,4S,6aR,7aS)-6-Amino-4-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)-1,1a,4,6a,7,7a-hexahydro-3H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one
Synonyms:(1aS,4S,6aR,7aS)-4-((1r,3R,5S,7S)-3,5-Dihydroxyadamantan-1-yl)-6-iminohexahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3(1aH)-one
CAS Number:1429782-93-3
Molecular Formula:C₁₈H₂₅N₃O₃
Molecular Weight:331.41
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(1aS,4S,6aR,7aS)-6-Amino-4-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)-1,1a,4,6a,7,7a-hexahydro-3H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one is a metabolite of Saxagliptin (S143500); a potent dipeptidyl peptidase-4 inhibitor approved for the treatment of type 2 diabetes mellitus.
References:Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008); Su, H., et al.: Drug Metab. Dispos., 40, 1345 (2012)
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