货号：E-2024062140
CAS：289472-80-6
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A622540
Chemical Name:N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Synonyms:N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; Bortezomib USP Impurity B
Impurity:Bortezomib USP Impurity B
CAS Number:289472-80-6
Molecular Formula:C₁₄H₁₄N₄O₂
Appearance:White to Off-White Solid
Melting Point:168-170°C
Molecular Weight:270.29
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.
References:Pekol, T., et al.: Drug. Meta. Disp., 33, 771 (2005); Hsieh, F.Y., et al.: J. Pharma. Biomed. Anal., 49, 115 (2009);
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