货号：E-2024062150
CAS：212498-37-8
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A622635
Chemical Name:2-(4-Aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid Methyl Ester Dihydrochloride (>90%)
Synonyms:2-(4-Aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid Methyl Ester Hydrochloride (1:2); T1032
CAS Number:212498-37-8
Molecular Formula:C₃₂H₃₁Cl₂N₃O₇
Appearance:White to Pale Beige Solid
Melting Point:>180ºC (dec.)
Molecular Weight:640.51
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Not Determined
Category:Standards; Enzyme Activators and Inhibitors;
Applications:2-(4-Aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxypheny Tl)-3-isoquinolinecarboxylic Acid Dihydrochloride, is a selective substrate for cytochrome P450 3A5 (CYP3A5). These compounds are also 4-Aryl-1-isoquinolinone Derivatives, which are shown to be novel, potent, and selective Phosphodiesterase 5 (PDE5) Inhibitors.
References:Song, X., et al.: Bio. Med. Chem. Lett., 22, 1611(2012); Tatsuzo, U., et al.: J. Med. Chem., 44, 2204 (2001);
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