货号：E-2024062307
CAS：870281-86-0
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A628755
Chemical Name:2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Synonyms:2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone; (S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propan-1-amine; (S)-2-(1-Aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;
CAS Number:870281-86-0
Molecular Formula:C₁₇H₁₆FN₃O
Appearance:Off-White Solid
Melting Point:166-169ºC
Molecular Weight:297.33
Storage:4°C, Hygroscopic
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.
References:Liu, J., et al.: Org. Prep. Proced. Int., 48, 337-341 (2016);
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