货号：E-2024062373
CAS：1849590-01-7
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A629153
Chemical Name:6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione
Synonyms:eFT508
CAS Number:1849590-01-7
Molecular Formula:C₁₇H₂₀N₆O₂
Appearance:Pale Yellow Solid
Melting Point:>300°C
Molecular Weight:340.38
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly, Heated), Methanol (Very Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione was used in the study of inhibitors of immune checkpoint modulators and related methods. eFT508 is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor.
References:Webster, K., et al.: U.S. Pat. Appl. Publ. (2016), US 20160303124 A1 20161020; Webster, K., et al.: Blood, 126, 1554 (2015);
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