货号：E-2024062377
CAS：129655-59-0
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A629168
Chemical Name:1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol
Synonyms:1-[(3-Aminoquinolin-4-yl)amino]-2-methylpropan-2-ol; 3-Amino-4-(2-hydroxy-2-methylpropylamino)quinoline
CAS Number:129655-59-0
Molecular Formula:C₁₃H₁₇N₃O
Appearance:Light Brown Solid
Melting Point:110-112°C
Molecular Weight:231.29
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Miscellaneous;
Applications:1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References:Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008)
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