货号：E-2024063258
CAS：520-36-5
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:A726500
Chemical Name:Apigenin
Synonyms:5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxyflavone; Pelargidenon 1449;
CAS Number:520-36-5
Molecular Formula:C₁₅H₁₀O₅
Appearance:Light Yellow to Dark Yellow Solid
Melting Point:>300°C (dec.)
Molecular Weight:270.24
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Research Tools; Enzyme Activators and Inhibitors;
Applications:Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.uv(max)ethanol: 269, 340 nm (e= 18,800, 20,900) moderately sol. in hot alcohol
References:Chaumontet, C., et al.: Carcinogenesis, 15, 2325 (1994); Sato, F., et al.: Biochem. Biophys. Res. Commun., 204, 578 (1994); Kuo, M.L. et al.: Biochem. Biophys. Res. Commun., 212, 767 (1995);
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